Recent research suggests ketamine infusion therapy works in providing rapid relief for 70% of patients suffering from treatment-resistant major depression, including a profound reduction in suicidal thoughts
Ketamine is a medication that was first developed in the 1960s as an anesthetic for surgical procedures. It is classified as a dissociative anesthetic, which means it can cause a feeling of detachment from oneself and the environment.
In addition to its use as an anesthetic, ketamine has been found to have other potential medical applications. For example, it has been used off-label to treat depression and chronic pain. It is thought to work by affecting the levels of certain neurotransmitters in the brain, such as glutamate and dopamine.
Are you struggling with a mood disorder such as depression, anxiety, or PTSD? You’re not alone. These conditions can be debilitating and impact every aspect of your life. Fortunately, there is hope. Ketamine, a medication that was originally developed as an anesthetic, has been found to be an effective treatment for mood disorders.
So, how does ketamine work to treat mood disorders? Ketamine affects certain neurotransmitters in the brain, including glutamate and dopamine, which are involved in regulating mood and emotions. By modulating these neurotransmitters, ketamine can rapidly alleviate symptoms of depression, anxiety, and PTSD, often within hours of administration.
Additionally, ketamine has been found to promote the growth of new neural connections in the brain, which can help improve overall brain function and resilience. This makes ketamine an effective treatment option for individuals who have not responded to traditional antidepressant medications or other treatments.
At Klarity, we offer ketamine therapy for mood disorder management in a safe and controlled clinical setting. Our team of experienced healthcare professionals will work with you to develop a personalized treatment plan that addresses your unique needs and concerns.
Don’t let a mood disorder control your life any longer. Contact us today to learn more about how ketamine therapy can help you find relief and regain control of your emotional wellbeing.
Are you struggling with chronic pain? You’re not alone. Millions of people suffer from chronic pain, a condition that can impact every aspect of your life. Fortunately, there is hope. Ketamine, a medication that was originally developed as an anesthetic, has been found to be an effective treatment for chronic pain.
So, how does ketamine work to treat chronic pain? Ketamine blocks certain receptors in the brain and spinal cord that are involved in pain signaling, which can reduce the amount of pain signals that are transmitted to the brain. This can result in significant pain relief for those suffering from chronic pain.
In addition to its pain-blocking properties, ketamine may also help reduce inflammation and improve blood flow, further contributing to pain relief. This makes ketamine an effective treatment option for a variety of chronic pain conditions, including neuropathic pain, complex regional pain syndrome, and fibromyalgia.
At Klarity, we offer ketamine therapy for chronic pain management in a safe and controlled clinical setting. Our team of experienced healthcare professionals will work with you to develop a personalized treatment plan that addresses your unique needs and concerns.
Don’t let chronic pain control your life any longer. Contact us today to learn more about how ketamine therapy can help you find relief and regain control of your life.
On the day of your procedure, you are not allowed to eat anything for 8 hours prior but you may continue to have a small amount of clear liquids (water, coffee without cream or sugar, tea, etc.) for up to 2 hours prior to your infusion.
When you arrive at Klarity, you will meet with one of our highly trained practitioners. You will be placed in a private room where an intravenous (IV) line will be started. Appropriate monitors, including blood pressure, oxygen saturation, and heart rate will be placed and the infusion begins.
You should feel the effects of Ketamine working quickly. You will not lose consciousness and should feel relaxed, as the dose of medication is well under the dose used in operating rooms. Some patients may experience a dissociative effect and partially lose awareness of their body. Many will find this out-of-body experience to be bizarre, but pleasurable.
The rate of the Ketamine infusion may be adjusted per patient to minimize any adverse symptoms. Typically the dissociative sensations resolve quickly after the infusion is completed. You must stay at the facility for up to 30 minutes after completion and you will need a driver to take you home as you are not allowed to drive the remainder of the day of your infusion.
During the ketamine infusion, you may experience changes in your mental state, such as feeling dissociated or detached from your surroundings. However, you will remain alert and able to communicate with our medical team throughout the treatment. Some patients have also reported temporary side effects like blurred vision, slurred speech, mental confusion, nausea, and vomiting. Rest assured that these effects are typically short-lived and resolve once the infusion is complete.
For your safety and the safety of others, it’s important to avoid driving, operating machinery, or making important decisions for the remainder of the day after your treatment. We require that you arrange for a responsible driver to take you home after your infusion, and ideally have someone stay with you for the rest of the day to monitor your condition.
At Klarity, we take great care to ensure that our patients receive the best possible care. Our team uses a comprehensive screening process, including various tests and assessments, to determine if ketamine infusions are a suitable treatment option for individuals with depression.
For patients who have not experienced relief from traditional antidepressant medications, ketamine infusions may offer a new and effective solution. Our medical team will work with you to determine if ketamine is the right choice for your individual needs and develop a personalized treatment plan that addresses your unique symptoms and concerns.
At Klarity, we understand the debilitating effects that mood disorders and chronic pain can have on your quality of life. If you’ve been struggling to find relief with traditional treatments, ketamine infusion therapy may be the solution you’ve been searching for. Our experienced medical team is dedicated to providing safe and effective ketamine treatments in a comfortable and supportive environment.
Don’t let depression, anxiety, PTSD, or chronic pain control your life any longer. Contact either of our locations in Indianapolis, IN, or Greenwood, IN, today to schedule a consultation and take the first step towards a happier, healthier you.
Ketamine infusion therapy is most helpful for those patients suffering treatment-resistant depression. For many, conventional antidepressants simply do not provide depression relief. Ketamine has been proven to rapidly reduce depression symptoms including suicidal thoughts and begin restoring life function for 70% of patients in less than 24 hours.
Ketamine infusions have also been shown to be effective for other conditions such as bipolar depression, post-traumatic stress disorder (PTSD), anxiety, obsessive compulsive disorder (OCD), fibromyalgia, and some pain disorders (CRPS).
Ketamine infusion therapy is NOT for those suffering temporary or situational depression caused by environmental factors, grief, relationship problems, etc. At Klarity, we treat those individuals that have been unresponsive to traditional medications and/or therapy over a sustained period of intense suffering and extreme physical impairment.
Ketamine is a drug approved by the FDA in 1970 for it’s ability to anesthetize patients quickly, safely, and with few side effects. It is only one of two anesthetics listed on the World Health Organization’s (WHO) Essential Drug List as it does not depress breathing and the circulatory system, unlike other anesthetics, and is fast-acting.
In recent years, ketamine’s use has broadened into the mental health field as it’s effect as an antidepressant has become one of the most widely researched topics in the field. Scientists at Yale made the breakthrough study published in Biological Psychiatry in 2000. Since then, numerous ongoing studies and clinical observations have established ketamine as a highly effective treatment for depression and other disorders.
Ketamine works by blocking the N-methyl-D-aspartate (NMDA) receptor, a component of the glutamate system that affects nearly all neurons. This is a different mechanism from most modern antidepressants that operate on other targets. Typical FDA-approved antidepressants target neurons that inhibit the reuptake of serotonin, norepinephrine, and dopamine. Brain scans reveal that ketamine rapidly induces synaptogenesis, repairing damage caused by chronic stress.
The patient will be in a private treatment room. They will be continuously monitored including blood pressure, heart rate, and oxygen saturation. An intravenous (IV) line will be placed and the infusion started. The infusion will be given slowly over 40 minutes. Many patients may find it helpful to listen to music or just sit back and relax. The IV will remain in place until the patient is fully recovered (typically 1-2 hours).
The patient should feel the effects of the ketamine quickly. They will not lose consciousness and should feel relaxed. Some patient may experience a dissociative effect, which is an out of body experience and partially lose awareness of their body. Most patients find this effect is a bizarre, but pleasurable experience. Typically, these dissociative sensations resolve quickly after the infusion is completed. The rate of the ketamine infusion can be adjusted per the individual patient to minimize adverse symptoms.
The relief will be different for every patient. Relief may take several hours or even several days to appear. This relief may be subtle. The patient may have an improvement in function prior to an improvement in mood. Function often improves before mood. There can be a spectrum of results.
There are several routes of administration of ketamine that include intravenous, intranasal, sublingual, intramuscular, orally, and rectally. The fastest route to the brain without being chemically altered is intravenous. When taken orally, the body metabolizes 84% of the ketamine. With intramuscular injection there is no control on the rate of uptake by the body. Intranasal administration can have a variable uptake by the body. Therefore, intravenous infusion of ketamine is the best route of administration.
Yes! Klarity is a consultant in your care. You will need to continue to follow-up with your primary physician who is managing your medical condition. We will work closely with your physician to best benefit your treatment course.
When administered to treat depression, ketamine is considered an “off-label” use since it is not FDA-approved for this purpose. Although recent research and clinical results have illustrated the overwhelmingly positive effects ketamine provides for the treatment of depression, FDA-approval requires extensive, very expensive trials. Since the drug itself is decades old and the patent expired a long time ago, Pharmaceutical companies that usually pay for these studies have no incentive to invest in getting ketamine approved for the treatment of depression.
Some may have heard of ketamine as a party drug under other names such as Special K, Kit Kat, or Vitamin K. However, ketamine has a wide safety margin in the hands of clinicians specially trained to administer the medication. The dose used for treatment of depression is less than the dose used for surgery. It has been found that at these very low doses, in a medical setting, there is virtually no potential for addiction or abuse.
Ketamine is generally safe when administered by a trained professional. Some patients may experience a dissociative effect, which is an out of body experience and partially lose awareness of their body. Ketamine is referred to as a dissociative anesthetic. However, doses used for depression are sub-anesthetic. Most patient feel sedated after their treatment, therefore will not be able to drive themselves home and should not plan any activities for the rest of the day. During the infusion, some patients may experience a temporary elevation in blood pressure and heart rate, which will be monitored continuously throughout the infusion. Other side effects include increased salivation, nystagmus or blurred vision, and nausea.
Most medications do not need to be stopped prior to treatment with ketamine. However, patients on benzodiazepines should work with their primary healthcare provider to stop these 2 weeks prior to treatment for optimal benefit of the the infusion.